Python constructor that initialize its parameters based on values from another python file

I have a class A and its constructor takes many variables. In my project, these variables are identified from another python file, B.

file B looks like this:

p1 = 4
p2 = 1
...
pN = 'dd'
#and a bunch of other variables.

Class A looks like this:

class A():
   def __init__(p1,p2,...,pN):

The number of parameters included in the constructor of A is very high, and I don't think it would be easy for a user (i.e., another one who wants to use my class) to initiate. However, I want my class to be generic and decoupled from other files in the project (i.e., file B). My question is how class A should be constructed?

A solution in my mind would be to pass the name of the python file that defines the parameters to a constructer in A:

class A():
   def __init__(self,python_filename):
       self.p1 = python_filename.p1
       self.p2 = python_filename.p2
   def __init__(self,p1,p2,...,pN):

My first thought is to make a class in B that has static members, would that be a good design in terms of being pythonic and object-oriented?